The two ideas give a bit other profile off anaphase separa- tion
This new Relatives regarding Mitosis and you will Meiosis (centered on Darlington). Observe that the newest chromosomes are twice at the its very first appearance for the mitosis, however regarding basic (leptotene) phase regarding meiotic prophase. It couple into the zygotene, start to be twice (split) from inside the pachytene, and they are twice over the last values away from meiotic prophase (diplotene and you can diakinesis). Inside mitosis anaphase begins of the department of your centromeres, however in meiosis this won’t can be found before the anaphase off another department (maybe not revealed). Darlington are the first one to suggest that if for example the parasynaptic interpre- tation is actually followed, all of the differences between meiosis and you may mitosis normally, with the aid of hardly any hypotheses, be deduced throughout the new difference in the singleness otherwise doubleness of your own prophase threads.
The guy suggested one homologous chromosomes, or in other words homologous chromonemata, focus both for the sets. So it appeal is met inside the mitotic prophase, however in early meiotic prophase, where the chromosomes are at first unmarried, and will simply satisfy the destination of the future together with her from inside the zygotene combining. In the meiosis, the latest spHtting of your own chromosomes, and that happens in the interphase ahead of an excellent mitotic division, does not happens right up until pachytene when the chromosomes seem to be relevant within the sets. They thus supplies a couple of five associated posts and they break apart to your diplotene loops, are stored together by the change out of mate during the chiasmata. Brand new losing apart of your own five posts was facts one to though two homologous chromosomes attract each other, you to definitely collection of homologous chromonemata repels some other similar couples.
Thus Darlington going your spUtting out of a beneficial chromosome in preparation for the next mitotic division takes place in the interphase just before that department, which new singleness of your meiotic chromo- somes is born in order to the point that it begin condensation and you will con- grip to the department till the splitting provides took place. Which hypo- thesis is named the latest Precocity Theory. A general change in the straightforward precocity principle has been proposed by the Huskins,^ exactly who welcomes Darhngton’s hypotheses the differences between the 2 forms away from office are due to brand new repulsion between pairs of chromonemata and you may destination ranging from unmarried chromonemata, however, denies Darlington’s account of one’s source of one’s singleness out of the newest meiotic chromosomes into the prophase. According to Huskins, brand new busting of chromosomes for starters office occurs while in the the previous department, forming a very-entitled tertiary split up which causes the chromo- specific pairs at the mitotic metaphase getting escort service Columbus actually quadripartite, those people in the meiotic metaphase octopartite regulators.
The fresh Mechanics Of CHROMOSOMES II5 evidence to get telosynapsis are adduced on density regarding continuing bands away from chromosomes from the meiotic metaphase in some organisms (mainly Oenothera), but several other a great deal more satisfactory explana- tion may now get because of it (p
For the interphase in advance of meiosis, so it tertiary spUt have to be allowed to be shed in a number of means, simply to getting restored at pachytene; within the diakinesis stage they ^ Cf. Huskins and you will Smith 1934. Il6 An overview of Modern Family genes try succeeded because of the other split towards the section hence comes after another meiotic section. Predicated on Darlington, the first separation of the chromo- somes in the anaphase is within mitosis because of the division from brand new centromeres at this point plus in meiosis in order to a heightened repulsion involving the centromeres hence today actually starts to beat the new pushes holding new chromosomes together with her in the chiasmata. Centered on Huskins, at exactly the same time, the new breakup of your own mitotic chromosomes is analogous on creation away from diplotene loops ; it’s a result of the synthesis of the fresh new tertiary split and this turns new matched up mitotic chromosomes towards the a set of mutually repelling coordinated posts.